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Kamberov Lab
Focus Areas:
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Genetic and developmental mechanisms underlying adaptive human sweat, hair, and mammary traits.
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Genetic and cellular interactions controlling identity, differentiation, and patterning of the eccrine sweat gland.
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Mechanisms of formation, action, and functional divergence of skin appendage mesenchymal niches.
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Regeneration of human eccrine sweat glands.
 Hair and sweat glands in mouse feet |  EDEN - mesenchymal niche of the developing eccrine sweat gland |  Developmental transcriptomes of the eccrine sweat gland epidermal program and its mesenchymal niche |
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 IF on adult human skin showing sweat gland secretory coils |  Section of adult human skin showing mautre eccrine sweat gland |  IF on developing human scalp skin showing eccrine sweat gland primordia next to mature hair follicle |
 Section of transgenic mouse skin showing enhancer activity in eccrine forming epidermis |  Expression of the eccrine identity determinant En1 in eccrine forming epidermis |  Mouse mammary gland tree with terminal end buds branching into the fat pad niche |
 Section of developing human skin showing eccrine primordium and associated EDEN niche (yellow) |  Human finger print with circular voids demarcating the openings of eccrine sweat glands |  Regulatory divergence explains the evolution of the human sweat gland phenotype |
 Stained section of rhesus macaque skin with multiple hair follicles and a single eccrine sweat glan |  Mature mouse eccrine glands in the ventral paw pads |
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